YOD1 anticorps (N-Term)

N° du produit ABIN2790891

L’anticorps Lapin Polyclonal anti-YOD1 a été validé pour WB. Il convient pour détecter YOD1 dans des échantillons de Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Boeuf (Vache).

Aperçu rapide pour YOD1 anticorps (N-Term) (ABIN2790891)

Antigène: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Reactivité: Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YOD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-YOD1 anticorps

Épitope: N-Term

Séquence: VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YOD1

Antigène: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Autre désignation: Yod1

Sujet: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343

Poids moléculaire: 37 kDa

ID gène: 226418

NCBI Accession: NM_178691, NP_848806

UniProt: Q8CB27

Pathways: ER-Nucleus Signaling