GRAP anticorps (N-Term)

N° du produit ABIN2791566

L’anticorps Lapin Polyclonal anti-GRAP a été validé pour WB. Il convient pour détecter GRAP dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Lapin, Chévre et Poisson zèbre (Danio rerio).

Aperçu rapide pour GRAP anticorps (N-Term) (ABIN2791566)

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Lapin, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRAP anticorps

Épitope: N-Term

Séquence: SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GRAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GRAP

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRAP

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Autre désignation: GRAP

Sujet: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Alias Symbols: -
Protein Interaction Partner: TRIM21, RBPMS, UBC, ARHGAP32, KHDRBS1, LAT, SHC1, SOS1, PLCG1, KIT, LCK, FYN, FASLG, EPOR, GAB2,
Protein Size: 217

Poids moléculaire: 25 kDa

ID gène: 10750

NCBI Accession: NM_006613, NP_006604

UniProt: Q13588