FANCD2 anticorps (Middle Region)

N° du produit ABIN2792058

Cet anticorps anti-FANCD2 Polyclonal Lapin (ABIN2792058) détecte spécifiquement FANCD2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Cheval et Porc.

Aperçu rapide pour FANCD2 anticorps (Middle Region) (ABIN2792058)

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reactivité: Humain, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FANCD2 anticorps

Épitope: Middle Region

Séquence: TPHTVTAISA KIRKKGKIER KQKTDGSKTS SSDTLSEEKN SECDPTPSHR

Homologie: Horse: 79%, Human: 100%, Pig: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FANCD2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FANCD2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FANCD2

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Autre désignation: FANCD2

Sujet: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
Alias Symbols: FA4, FAD, FACD, FAD2, FA-D2, FANCD
Protein Size: 749

Poids moléculaire: 82 kDa

ID gène: 2177

NCBI Accession: NM_001018115, NP_001018125

UniProt: Q9BXW9

Pathways: Réparation de l'ADN