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FANCD2 anticorps (Fanconi Anemia, Complementation Group D2) Middle Region Primary Antibody

FANCD2 Reactivité: Humain, Cheval, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792058
$389.00
Plus shipping costs $45.00
100 μL
Destination: Etats-Unis
Envoi sous 2 à 3 jours ouvrables
  • Antigène Voir toutes FANCD2 Anticorps
    FANCD2
    Épitope
    • 16
    • 15
    • 14
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 102
    • 28
    • 24
    • 1
    Humain, Cheval, Porc
    Hôte
    • 100
    • 3
    Lapin
    Clonalité
    • 91
    • 12
    Polyclonal
    Conjugué
    • 35
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp FANCD2 est non-conjugé
    Application
    • 39
    • 27
    • 27
    • 26
    • 22
    • 19
    • 12
    • 9
    • 7
    • 6
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    TPHTVTAISA KIRKKGKIER KQKTDGSKTS SSDTLSEEKN SECDPTPSHR
    Homologie
    Horse: 79%, Human: 100%, Pig: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against FANCD2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human FANCD2
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    FANCD2
    Autre désignation
    FANCD2 (FANCD2 Produits)
    Synonymes
    FANCD2, CG17269, CG31192, CG31194, Dmel\\CG17269, dmFANCD2, xfancd2, FA-D2, FA4, FACD, FAD, FAD2, FANCD, 2410150O07Rik, AU015151, BB137857, Fanconi anemia complementation group D2, CG17269 gene product from transcript CG17269-RA, Fanconi anemia group D2 protein, Fanconi anemia, complementation group D2, Fanconi anemia complementation group D2 L homeolog, FANCD2, Fancd2, LOC100455970, fancd2, fancd2.L
    Sujet
    The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
    Alias Symbols: FA4, FAD, FACD, FAD2, FA-D2, FANCD
    Protein Size: 749
    Poids moléculaire
    82 kDa
    ID gène
    2177
    NCBI Accession
    NM_001018115, NP_001018125
    UniProt
    Q9BXW9
    Pathways
    Réparation de l'ADN
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