TXN anticorps (C-Term)

N° du produit ABIN2792061

Cet anticorps anti-TXN est un anticorps Lapin Polyclonal détectant TXN dans WB et IHC. Adapté pour Humain, Rat, Souris, Boeuf (Vache), Porc, Lapin, Chien, Cobaye, Cheval et Mouton.

Aperçu rapide pour TXN anticorps (C-Term) (ABIN2792061)

Antigène: TXN (Thioredoxin (TXN))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Lapin, Chien, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TXN anticorps

Épitope: C-Term

Séquence: NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TXN

Antigène: TXN (Thioredoxin (TXN))

Autre désignation: TXN

Sujet: TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)
Alias Symbols: TRDX, TRX, TRX1
Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S
Protein Size: 105

Poids moléculaire: 11 kDa

ID gène: 7295

NCBI Accession: NM_003329, NP_003320

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis