14-3-3 theta anticorps (N-Term)

N° du produit ABIN2792144

L’anticorps Lapin Polyclonal anti-14-3-3 theta a été validé pour WB et IHC. Il convient pour détecter 14-3-3 theta dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour 14-3-3 theta anticorps (N-Term) (ABIN2792144)

Antigène: 14-3-3 theta (YWHAQ)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 theta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-14-3-3 theta anticorps

Épitope: N-Term

Séquence: SVAYKNVVGG RRSAWRVISS IEQKTDTSDK KLQLIKDYRE KVESELRSIC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against YWHAQ. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 245 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur 14-3-3 theta

Antigène: 14-3-3 theta (YWHAQ)

Autre désignation: YWHAQ

Sujet: YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Alias Symbols: 1C5, HS1, 14-3-3
Protein Interaction Partner: UBC, TNFAIP3, TRIM42, RAF1, PIK3R2, PIK3C3, FUS, DTL, MAPT, ABL1, SGK1, SIK3, SUMO2, TUBGCP3, IRS4, HDAC5, HDAC4, STAU1, MDM2, TGM2, SMS, ALDH7A1, YWHAZ, YWHAH, GNAI3, G6PD, EIF5, EEF2, ECHS1, CAPNS1, CAPN1, LDHB, YWHAG, YWHAB, VCL, UBE2V1, TXNDC5, SMEK2,
Protein Size: 245

Poids moléculaire: 28 kDa

ID gène: 10971

NCBI Accession: NM_006826, NP_006817

UniProt: P27348

Pathways: Apoptose, Myometrial Relaxation and Contraction