Cyclin D3 anticorps (C-Term)

N° du produit ABIN2792167

Détail du produit anti-Cyclin D3 anticorps

Antigène: Cyclin D3 (CCND3)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: CQEQIEAALR ESLREASQTS SSPAPKAPRG SSSQGPSQTS TPTDVTAIHL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CCND3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 292 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: CCND3 (CCND3 Produits)

Synonymes: anticorps zgc:103502, anticorps CCND3, anticorps 9230106B05Rik, anticorps AA682053, anticorps AL024085, anticorps AW146355, anticorps C78795, anticorps cyclin D3, anticorps ccnd3, anticorps CCND3, anticorps Ccnd3

Sujet: CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
Protein Interaction Partner: POLR3GL, TFIP11, CDKN1A, CDK6, CDK4, CDK5, MCM10, CDKN1B, CDK2, CDK11B, FAS, SIL1, EIF3K, ATF5, VDR, MAPK6, NME1, MYB, GC, ETV1, RBL2, POLD1, CDK14, APP, RB1, UBC, PPP1CC, PPP1CB, PPP1CA, NCOA2, MAF1, NPDC1, DMTF1, CRABP2, RARA, DTNBP1, AKAP8, EFEMP2, CAS
Protein Size: 292

Poids moléculaire: 33 kDa

ID gène: 896

NCBI Accession: NM_001760, NP_001751

UniProt: P30281

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process