CDK8 anticorps (C-Term)
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- Antigène Voir toutes CDK8 Anticorps
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Boeuf (Vache), Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CDK8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8
- Top Product
- Discover our top product CDK8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 464 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Autre désignation
- CDK8 (CDK8 Produits)
- Synonymes
- anticorps K35, anticorps wu:fk95h11, anticorps cyclin dependent kinase 8, anticorps cyclin-dependent kinase 8, anticorps cyclin-dependent kinase 8 S homeolog, anticorps Cyclin-dependent kinase 8, anticorps cyclin dependent kinase 19, anticorps CDK8, anticorps Cdk8, anticorps cdk8, anticorps cdk8.S, anticorps cdk-8, anticorps CDK19
- Sujet
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The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
Alias Symbols: K35
Protein Interaction Partner: CCNC, MED18, MED15, MED31, MED4, MED13L, MED16, MED6, MED13, MED12, MED24, MED20, MED7, MED27, MED17, MED23, MED21, MED14, HERC2, MED22, MED1, MED11, MED8, MED30, MED10, MED28, MED29, MED9, HNRNPF, CDK8, ERCC3, CCNH, MED19, TCEA1, MBP, CTD, MED26, POLR2A,
Protein Size: 464 - Poids moléculaire
- 53 kDa
- ID gène
- 1024
- NCBI Accession
- NM_001260, NP_001251
- UniProt
- P49336
- Pathways
- Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha
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