CDK8 anticorps (C-Term)

N° du produit ABIN2792177

Cet anticorps anti-CDK8 Polyclonal Lapin (ABIN2792177) détecte spécifiquement CDK8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Boeuf (Vache) et Porc.

Aperçu rapide pour CDK8 anticorps (C-Term) (ABIN2792177)

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Reactivité: Humain, Souris, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK8 anticorps

Épitope: C-Term

Fonction: CDK8 Antibody - C-terminal region

Séquence: GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDK8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK8

Antigène: CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

Autre désignation: CDK8

Sujet:

Background Information: The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.

Gene Name: Cyclin-dependent kinase 8

Alternative Symbols: K35, IDDHBA

Protein Name: Cyclin-dependent kinase 8

Poids moléculaire: 53kDa

ID gène: 1024

NCBI Accession: NP_001251

UniProt: P49336

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha