CXCR6 anticorps (N-Term)
Aperçu rapide pour CXCR6 anticorps (N-Term) (ABIN487291)
Antigène
Voir toutes CXCR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- AEHDYHEDYG FSSFNDSSQE EHQDFLQFSK VFLPCMYLVV FVCGLVGNSL
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CXCR6. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR6
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 342 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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Autre désignation
- CXCR6
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Sujet
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CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.
Alias Symbols: BONZO, CD186, STRL33, TYMSTR
Protein Interaction Partner: CXCL16,
Protein Size: 342 -
Poids moléculaire
- 39 kDa
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ID gène
- 10663
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NCBI Accession
- NM_006564, NP_006555
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UniProt
- O00574
Antigène
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