HSPD1 anticorps (C-Term)

N° du produit ABIN2792215

Cet anticorps anti-HSPD1 est un anticorps Lapin Polyclonal détectant HSPD1 dans WB. Adapté pour Humain, Rat, Lapin et Cobaye.

Aperçu rapide pour HSPD1 anticorps (C-Term) (ABIN2792215)

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reactivité: Humain, Rat, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HSPD1 anticorps

Épitope: C-Term

Séquence: PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG

Homologie: Guinea Pig: 90%, Human: 84%, Rabbit: 84%, Rat: 84%

Attributs du produit: This is a rabbit polyclonal antibody against HSPD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 573 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HSPD1

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Autre désignation: HSPD1

Sujet: HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Alias Symbols: CPN60, GROEL, HSP60, HSP65, HuCHA60, SPG13, HLD4, HSP-60
Protein Interaction Partner: RGS20, NOTCH2NL, KRTAP10-3, KRTAP10-8, SAMD3, KRT40, LZTS2, CEP70, HUWE1, TMCC2, KRT31, KRTAP5-9, FUS, TUBGCP3, AURKB, VCP, UBC, TUBG1, AURKA, SUMO3, LGALS3BP, CDC20, STAU1, LGR4, NEDD8, MDM2, ERG, ASB4, EED, MAPK14, ATP6V1A, RAB1B, C12orf10, NAGK, C11orf
Protein Size: 573

Poids moléculaire: 61 kDa

ID gène: 3329

NCBI Accession: NM_002156, NP_002147

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity