Caveolin 2 anticorps (N-Term)

N° du produit ABIN2792220

Il existe 1 publication pour ce produit. L’anticorps anti-Caveolin 2 Polyclonal Lapin est utilisé pour la détection de Caveolin 2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Mouton et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour Caveolin 2 anticorps (N-Term) (ABIN2792220)

Antigène: Caveolin 2 (CAV2)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Mouton, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Caveolin 2 anticorps

Épitope: N-Term

Fonction: CAV2 Antibody - N-terminal region

Séquence: LVIPYNEKPE KPAKTQKTSL DEALQWRDSL DKLLQNNYGL ASFKSFLKSE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CAV2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CAV2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Caveolin 2 (ABIN2792220)

Chi Sabins, Taylor, Fabian, Appleman, Maranchie, Stolz, Storkus: "DLK1: a novel target for immunotherapeutic remodeling of the tumor blood vasculature." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 21, Issue 10, pp. 1958-68, (2013) (PubMed).

Détails sur Caveolin 2

Antigène: Caveolin 2 (CAV2)

Autre désignation: CAV2

Sujet:

Background Information: CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

Gene Name: Caveolin 2

Alternative Symbols: CAV

Protein Name: Caveolin-2

Poids moléculaire: 18kDa

ID gène: 858

NCBI Accession: NP_001224

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development