SFRP1 anticorps (Middle Region)

N° du produit ABIN2792235

Cet anticorps Lapin Polyclonal détecte spécifiquement SFRP1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval et Cobaye et a été mentionné dans 1 publication.

Aperçu rapide pour SFRP1 anticorps (Middle Region) (ABIN2792235)

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SFRP1 anticorps

Épitope: Middle Region

Séquence: HQLDNLSHHF LIMGRKVKSQ YLLTAIHKWD KKNKEFKNFM KKMKNHECPT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SFRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SFRP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 314 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SFRP1 (ABIN2792235)

Qiu, Xu, Zhou, Shi, Ma, Li, Li: "Involvement of genetic instability in the downregulation of sFRP1 in Chinese patients with hepatocellular carcinoma." dans: Anatomical record (Hoboken, N.J. : 2007), Vol. 293, Issue 12, pp. 2020-6, (2010) (PubMed).

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: SFRP1

Sujet: Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 may be involved in de
Alias Symbols: FRP, FRP1, FrzA, FRP-1, SARP2
Protein Interaction Partner: KIAA1522, PPP1CC, PPP1CA, WNT4, FZD6, WNT1, WNT2,
Protein Size: 314

Poids moléculaire: 35 kDa

ID gène: 6422

NCBI Accession: NM_003012, NP_003003

UniProt: Q8N474

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation