CCR8 anticorps (Middle Region)

N° du produit ABIN2792241

Cet anticorps anti-CCR8 Polyclonal Lapin (ABIN2792241) détecte spécifiquement CCR8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache) et Lapin.

Aperçu rapide pour CCR8 anticorps (Middle Region) (ABIN2792241)

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivité: Humain, Boeuf (Vache), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCR8 anticorps

Épitope: Middle Region

Fonction: CCR8 Antibody - middle region

Séquence: MATIPLLVFY QVASEDGVLQ CYSFYNQQTL KWKIFTNFKM NILGLLIPFT

Homologie: Cow: 93%, Human: 100%, Rabbit: 81%

Attributs du produit: This is a rabbit polyclonal antibody against CCR8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CCR8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CCR8

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Autre désignation: CCR8

Sujet:

Background Information: CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.

Gene Name: Chemokine (C-C motif) receptor 8

Alternative Symbols: CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8

Protein Name: C-C chemokine receptor type 8

Poids moléculaire: 41kDa

ID gène: 1237

NCBI Accession: NP_005192

UniProt: P51685