CHM anticorps (N-Term)

N° du produit ABIN2792245

Il existe 1 publication pour ce produit. L’anticorps anti-CHM Polyclonal Lapin est utilisé pour la détection de CHM dans des échantillons de Humain et Cheval. Il a été validé pour WB.

Aperçu rapide pour CHM anticorps (N-Term) (ABIN2792245)

Antigène: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHM anticorps

Épitope: N-Term

Fonction: CHM Antibody - N-terminal region

Séquence: LHVDSRSYYG GNWASFSFSG LLSWLKEYQE NSDIVSDSPV WQDQILENEE

Homologie: Horse: 80%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CHM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CHM (ABIN2792245)

Ishiguro, Yamamoto, Fujita, Akasu, Kobayashi, Moriya: "Effect of a clinical pathway after laparoscopic surgery for colorectal cancer." dans: Hepato-gastroenterology, Vol. 55, Issue 85, pp. 1315-9, (2008) (PubMed).

Détails sur CHM

Antigène: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Autre désignation: CHM

Sujet:

Background Information: CHM binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.The choroideremia gene encodes for a protein, the Rab escort protein-1 (REP1), which is involved in membrane trafficking.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Choroideremia (Rab escort protein 1)

Alternative Symbols: TCD, GGTA, REP-1, DXS540, HSD-32

Protein Name: Rab proteins geranylgeranyltransferase component A 1

Poids moléculaire: 73kDa

ID gène: 1121

NCBI Accession: NP_000381

UniProt: P24386

Pathways: Sensory Perception of Sound