SMAD3 anticorps (N-Term)

N° du produit ABIN2792537

Cet anticorps Lapin Polyclonal détecte spécifiquement SMAD3 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien et Cobaye.

Aperçu rapide pour SMAD3 anticorps (N-Term) (ABIN2792537)

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SMAD3 anticorps

Épitope: N-Term

Séquence: FTPPIVKRLL GWKKGEQNGQ EEKWCEKAVK SLVKKLKKTG QLDELEKAIT

Réactivité croisée: Chien, Poulet, Humain, Souris, Porc, Rat (Rattus)

Homologie: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD3

Information d'application

Indications d'application: WB Suggested Anti-SMAD3 Antibody Titration: 2.0 µg/mL
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 425 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD3

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: SMAD3

Sujet: SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.
Alias Symbols: LDS1C, MADH3, JV15-2, HSPC193, HsT17436
Protein Interaction Partner: TEKT4, CCDC33, CPSF7, MEOX2, HDAC1, PHC2, WWP1, AES, BLZF1, UBC, TP53, SMAD4, BACH1, MAFK, FOXO3, NEDD8, TRIM33, WWP2, SMURF2, FOXM1, TRIM62, TP63, OTUB1, NEDD4L, BAG3, TGFB1I1, CSNK1D, RUNX1, HCVgp1, TSC2, FHL3, FHL2, FHL1, Melk, IRF7, RNF111, LCK, KLF5,
Protein Size: 425

Poids moléculaire: 48 kDa

ID gène: 4088

NCBI Accession: NM_005902, NP_005893

UniProt: Q92940

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy