SMAD3 anticorps (N-Term)

N° du produit ABIN2792537

Détail du produit anti-SMAD3 anticorps

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FTPPIVKRLL GWKKGEQNGQ EEKWCEKAVK SLVKKLKKTG QLDELEKAIT

Réactivité croisée: Chien, Poulet, Humain, Souris, Porc, Rat (Rattus)

Homologie: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SMAD3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD3

Information d'application

Indications d'application: WB Suggested Anti-SMAD3 Antibody Titration: 2.0 µg/mL
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 425 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMAD3

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: SMAD3 (SMAD3 Produits)

Synonymes: anticorps HSPC193, anticorps HsT17436, anticorps JV15-2, anticorps LDS1C, anticorps LDS3, anticorps MADH3, anticorps madh3, anticorps madh3a, anticorps smad3, anticorps wu:fa99e03, anticorps XSmad3, anticorps XenMLP, anticorps Xmad3, anticorps madh3-A, anticorps Madh3, anticorps AU022421, anticorps Smad 3, anticorps mad3, anticorps madh3b, anticorps zgc:92234, anticorps SMAD family member 3, anticorps SMAD family member 3a, anticorps SMAD family member 3 L homeolog, anticorps SMAD family member 3b, anticorps SMAD3, anticorps smad3a, anticorps smad3.L, anticorps Smad3, anticorps smad3b

Sujet: SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.
Alias Symbols: LDS1C, MADH3, JV15-2, HSPC193, HsT17436
Protein Interaction Partner: TEKT4, CCDC33, CPSF7, MEOX2, HDAC1, PHC2, WWP1, AES, BLZF1, UBC, TP53, SMAD4, BACH1, MAFK, FOXO3, NEDD8, TRIM33, WWP2, SMURF2, FOXM1, TRIM62, TP63, OTUB1, NEDD4L, BAG3, TGFB1I1, CSNK1D, RUNX1, HCVgp1, TSC2, FHL3, FHL2, FHL1, Melk, IRF7, RNF111, LCK, KLF5,
Protein Size: 425

Poids moléculaire: 48 kDa

ID gène: 4088

NCBI Accession: NM_005902, NP_005893

UniProt: Q92940

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy