SOX8 anticorps (C-Term)

N° du produit ABIN2792566

Cet anticorps Lapin Polyclonal détecte spécifiquement SOX8 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour SOX8 anticorps (C-Term) (ABIN2792566)

Antigène: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SOX8 anticorps

Épitope: C-Term

Séquence: ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP

Réactivité croisée: Chien, Humain, Souris, Rat (Rattus)

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8

Information d'application

Indications d'application: WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 446 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOX8

Antigène: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Autre désignation: SOX8

Sujet: SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Alias Symbols: MGC24837
Protein Interaction Partner: JAM2, PIDD1, NOD1, UBC, MMP1, SOX2, HOXC11, UTF1, PAX3, OLIG2, HHEX, POU3F3, TCF12, DLX5, SP1, NR5A1, JUN, POU5F1, EGR2, CEBPA,
Protein Size: 446

Poids moléculaire: 47 kDa

ID gène: 30812

NCBI Accession: NM_014587, NP_055402

UniProt: P57073

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development