RORA anticorps (N-Term)

N° du produit ABIN2792585

L’anticorps anti-RORA Polyclonal Lapin est utilisé pour la détection de RORA dans des échantillons de Humain et Boeuf (Vache). Il a été validé pour WB.

Aperçu rapide pour RORA anticorps (N-Term) (ABIN2792585)

Antigène: RORA (RAR-Related Orphan Receptor A (RORA))

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RORA anticorps

Épitope: N-Term

Fonction: RORA Antibody - N-terminal region

Séquence: ARKSEPPAPV RRQSYSSTSR GISVTKKTHT SQIEIIPCKI CGDKSSGIHY

Réactivité croisée: Humain

Homologie: Cow: 100%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RORA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RORA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORA

Antigène: RORA (RAR-Related Orphan Receptor A (RORA))

Autre désignation: RORA

Sujet:

Background Information: RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

Gene Name: RAR-related orphan receptor A

Alternative Symbols: ROR1, ROR2, ROR3, RZRA, NR1F1, IDDECA, RZR-ALPHA

Protein Name: Retinoid-related orphan receptor alpha EMBL BAH02285.1

Poids moléculaire: 59kDa

ID gène: 6095

NCBI Accession: NP_599023

UniProt: B6ZGS4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha