DP1 anticorps (N-Term)
Aperçu rapide pour DP1 anticorps (N-Term) (ABIN2792602)
Antigène
Voir toutes DP1 (TFDP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- VIGTPQRPAA SNTLVVGSPH TPSTHFASQN QPSDSSPWSA GKRNRKGEKN
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Réactivité croisée
- Boeuf (Vache), Humain, Souris, Rat (Rattus)
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Homologie
- Cow: 92%, Human: 100%, Mouse: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against TFDP1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TFDP1
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Indications d'application
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WB Suggested Anti-TFDP1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator. -
Commentaires
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Antigen size: 410 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
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Autre désignation
- TFDP1
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Sujet
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The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors and may have a role in progression of some hepatocellular carcinomas by promoting growth of the tumor cells.
Alias Symbols: DP1, Dp-1, DRTF1
Protein Interaction Partner: UBC, E2F6, E2F4, SIAH1, E2F3, E2F2, E2F1, CDK6, PRPF31, CDK2, CDK1, SOCS3, RB1, PCGF6, RYBP, YAF2, RNF2, ELAVL1, LIN9, LIN54, LIN37, RBL2, SERTAD2, NPDC1, E2F5, TP53, RBL1, CDK3, TP53BP1,
Protein Size: 410 -
Poids moléculaire
- 45 kDa
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ID gène
- 7027
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NCBI Accession
- NM_007111, NP_009042
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UniProt
- Q14186
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Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
Antigène
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