POU3F2 anticorps (C-Term)
Aperçu rapide pour POU3F2 anticorps (C-Term) (ABIN2792618)
Antigène
Voir toutes POU3F2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QLEKEVVRVW FCNRRQKEKR MTPPGGTLPG AEDVYGGSRD TPPHHGVQTP
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Réactivité croisée
- Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
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Homologie
- Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against POU3F2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human POU3F2
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Indications d'application
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WB Suggested Anti-POU3F2 Antibody Titration: 0.2-1 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator. -
Commentaires
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Antigen size: 443 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
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Autre désignation
- POU3F2
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Sujet
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N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1, MIM 164175) and Oct2 (POU2F2, MIM 164176), and the pituitary protein Pit1 (PIT1, MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Alias Symbols: BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7
Protein Interaction Partner: UBC, TBP, SOX10, POU3F2, PAX3, GTF2B, EP300, SOX11, PQBP1, POU3F4,
Protein Size: 443 -
Poids moléculaire
- 47 kDa
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ID gène
- 5454
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NCBI Accession
- NM_005604, NP_005595
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UniProt
- P20265
Antigène
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