MAP3K4 anticorps (AA 235-264)

N° du produit ABIN2793281

L’anticorps Lapin Polyclonal anti-MAP3K4 a été validé pour IHC et WB. Il convient pour détecter MAP3K4 dans des échantillons de Humain.

Aperçu rapide pour MAP3K4 anticorps (AA 235-264) (ABIN2793281)

Antigène: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K4 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-MAP3K4 anticorps

Épitope: AA 235-264

Fonction: Rabbit Anti-Human MEKK4 (MAP2K4) (S257) Antibody

Immunogène: This MEKK4(MAP2K4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from human MEKK4(MAP2K4).

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of MAP2K4 (arrow) using rabbit polyclonal MAP2K4 Antibody (S257) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.350 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur MAP3K4

Antigène: MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

Autre désignation: MEKK4

Sujet:

Target Description: MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.

Gene Symbol: MAP2K4

Poids moléculaire: 44288 Da

ID gène: 6416

UniProt: P45985

Pathways: Signalisation MAPK