PRKD3 anticorps (C-Term)

N° du produit ABIN2795131

Cet anticorps Lapin Polyclonal détecte spécifiquement PRKD3 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PRKD3 anticorps (C-Term) (ABIN2795131)

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PRKD3 anticorps

Épitope: AA 860-890, C-Term

Fonction: Rabbit Anti-Human PKC nu (C-term) Antibody

Immunogène: This PKC nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 860-890 amino acids from the C-terminal region of human PKC nu.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-PKCnu C-term Pab antibodies. Lower panel, indirect immunofluorescence analysis of GFP-PKD3 fusion protein expression in Panc-1 cells by using 102-17077 and 102-17078 antibodies. Data courtesy of Dr. Osvaldo Rey, University of California Los Angeles.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.710 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PRKD3

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Autre désignation: PKC nu

Sujet:

Target Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Gene Symbol: PRKD3

Poids moléculaire: 100471 Da

ID gène: 23683

UniProt: O94806