APC anticorps (Center) (APC)
Aperçu rapide pour APC anticorps (Center) (APC) (ABIN2795685)
Antigène
Voir toutes APC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1148-1176, Center
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Fonction
- Rabbit Anti-Mouse APC (Center) Antibody
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Immunogène
- This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000APC Antibody (Center). -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- APC (Adenomatous Polyposis Coli (APC))
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Autre désignation
- APC
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Sujet
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Target Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Gene Symbol: APC
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Poids moléculaire
- 311646 Da
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ID gène
- 324
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UniProt
- P25054
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Pathways
- Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization
Antigène
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