KISS1 anticorps (Center)

N° du produit ABIN2796067

Cet anticorps Lapin Polyclonal détecte spécifiquement KISS1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour KISS1 anticorps (Center) (ABIN2796067)

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KISS1 anticorps

Épitope: AA 235-263, Center

Fonction: Rabbit Anti-Human KISS1R (Center) Antibody

Immunogène: This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000KISS1R Antibody (Center) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.650 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur KISS1

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Autre désignation: KISS1

Sujet:

Target Description: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Gene Symbol: KISS1R

Poids moléculaire: 42586 Da

ID gène: 84634

UniProt: Q969F8

Pathways: Positive Regulation of Peptide Hormone Secretion