USP2 anticorps (N-Term)

N° du produit ABIN2796342

Cet anticorps anti-USP2 est un anticorps Lapin Polyclonal détectant USP2 dans WB, IHC et ISt. Adapté pour Humain.

Aperçu rapide pour USP2 anticorps (N-Term) (ABIN2796342)

Antigène: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunostaining (ISt)

Détail du produit anti-USP2 anticorps

Épitope: AA 71-101, N-Term

Fonction: Rabbit Anti-Human USP2 (N-term) Antibody

Immunogène: This USP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-101 amino acids from the N-terminal region of human USP2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of USP2 Antibody (N-term) with the USP2 gene.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur USP2

Antigène: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Autre désignation: USP2

Sujet:

Target Description: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Gene Symbol: USP2

Poids moléculaire: 68072 Da

ID gène: 9099

UniProt: O75604