KREMEN2 anticorps (Center)
Aperçu rapide pour KREMEN2 anticorps (Center) (ABIN2798011)
Antigène
Voir toutes KREMEN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 248-276, Center
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Fonction
- Rabbit Anti-Human KREMEN2 (Center) Antibody
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Immunogène
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000KREMEN2 Antibody (Center) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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Autre désignation
- KREMEN2
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Sujet
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Target Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Gene Symbol: KREMEN2
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Poids moléculaire
- 48849 Da
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ID gène
- 79412
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UniProt
- Q8NCW0
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Pathways
- Signalisation WNT
Antigène
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