TERT anticorps (Center)

N° du produit ABIN2798432

L’anticorps Lapin Polyclonal anti-TERT a été validé pour WB, FACS et IF. Il convient pour détecter TERT dans des échantillons de Humain.

Aperçu rapide pour TERT anticorps (Center) (ABIN2798432)

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TERT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-TERT anticorps

Épitope: AA 627-656, Center

Fonction: Rabbit Anti-Human TERT (Center) Antibody

Immunogène: This TERT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the Central region of human TERT.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-TERT Antibody (Center) (RB14069) in Jurkat cell line lysates (35 μg/lane). TERT(arrow) was detected using the purified Pab.TERT Antibody (Center) . TERT immunoreactivity is localized to Nucleus significantly and Cytoplasm weakly.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur TERT

Antigène: TERT (Telomerase Reverse Transcriptase (TERT))

Autre désignation: TERT

Sujet:

Target Description: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

Gene Symbol: TERT

Poids moléculaire: 126997 Da

ID gène: 7015

UniProt: O14746

Pathways: Telomere Maintenance