Cofilin 2 anticorps (N-Term)

N° du produit ABIN2798438

L’anticorps Lapin Polyclonal anti-Cofilin 2 a été validé pour WB et IHC. Il convient pour détecter Cofilin 2 dans des échantillons de Humain.

Aperçu rapide pour Cofilin 2 anticorps (N-Term) (ABIN2798438)

Antigène: Cofilin 2 (CFL2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Cofilin 2 anticorps

Épitope: AA 25-54, N-Term

Fonction: Rabbit Anti-Human CFL2 (N-term) Antibody

Immunogène: This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from NCI-H1299 cell line, using CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.480 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: CFL2

Sujet:

Target Description: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Gene Symbol: CFL2

Poids moléculaire: 18737 Da

ID gène: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis