PRDM6 anticorps (N-Term)

N° du produit ABIN2798584

Cet anticorps Lapin Polyclonal détecte spécifiquement PRDM6 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PRDM6 anticorps (N-Term) (ABIN2798584)

Antigène: PRDM6 (PR Domain Containing 6 (PRDM6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRDM6 anticorps

Épitope: AA 44-72, N-Term

Fonction: Rabbit Anti-Human PRDM6 (N-term) Antibody

Immunogène: This PRDM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human PRDM6.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000PRDM6 Antibody (N-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.350 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PRDM6

Antigène: PRDM6 (PR Domain Containing 6 (PRDM6))

Autre désignation: PRDM6

Sujet:

Target Description: Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

Gene Symbol: PRDM6

Poids moléculaire: 64452 Da

ID gène: 93166

UniProt: Q9NQX0

Pathways: Regulation of Muscle Cell Differentiation