RPA1 anticorps (C-Term)

N° du produit ABIN2798585

L’anticorps Lapin Polyclonal anti-RPA1 a été validé pour WB. Il convient pour détecter RPA1 dans des échantillons de Humain.

Aperçu rapide pour RPA1 anticorps (C-Term) (ABIN2798585)

Antigène: RPA1 (Replication Protein A1, 70kDa (RPA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RPA1 anticorps

Épitope: AA 531-559, C-Term

Fonction: Rabbit Anti-Human RPA1 (C-term) Antibody

Immunogène: This RPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human RPA1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000RPA1 Antibody (C-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur RPA1

Antigène: RPA1 (Replication Protein A1, 70kDa (RPA1))

Autre désignation: RPA1

Sujet:

Target Description: RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Gene Symbol: RPA1

Poids moléculaire: 68138 Da

ID gène: 6117

UniProt: P27694

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA