KDM5B anticorps (N-Term)

N° du produit ABIN2798607

Cet anticorps anti-KDM5B Polyclonal Lapin (ABIN2798607) détecte spécifiquement KDM5B dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour KDM5B anticorps (N-Term) (ABIN2798607)

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KDM5B anticorps

Épitope: AA 192-224, N-Term

Fonction: Rabbit Anti-Mouse JARID1B (N-term) Antibody

Immunogène: This JARID1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000JARID1B Antibody (N-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.410 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur KDM5B

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Autre désignation: JARID1B

Sujet:

Target Description: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.

Gene Symbol: KDM5B

Poids moléculaire: 175658 Da

ID gène: 10765

UniProt: Q9UGL1

Pathways: L'effet Warburg