LIN28B anticorps (Center)

N° du produit ABIN2798789

L’anticorps Lapin Polyclonal anti-LIN28B a été validé pour WB, IHC, FACS et IF. Il convient pour détecter LIN28B dans des échantillons de Humain.

Aperçu rapide pour LIN28B anticorps (Center) (ABIN2798789)

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN28B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-LIN28B anticorps

Épitope: AA 95-128, Center

Fonction: Rabbit Anti-Human LIN28B (Center) Antibody

Immunogène: This LIN28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-128 amino acids from the Central region of human LIN28B.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50, IF: 1:10-50Western blot analysis of anti-LIN28B Pab .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.500 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur LIN28B

Antigène: LIN28B (Lin-28 Homolog B (LIN28B))

Autre désignation: LIN28B

Sujet:

Target Description: Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.

Gene Symbol: LIN28B

Poids moléculaire: 27084 Da

ID gène: 389421

UniProt: Q6ZN17