MXI1 anticorps (Center)
Aperçu rapide pour MXI1 anticorps (Center) (ABIN2798843)
Antigène
Voir toutes MXI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 53-82, Center
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Fonction
- Rabbit Anti-Mouse MXI1 (Center) Antibody
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Immunogène
- This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000MXI1 Antibody (Center) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- MXI1 (MAX Interactor 1 (MXI1))
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Autre désignation
- MXI1
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Sujet
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Target Description: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Gene Symbol: MXI1
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Poids moléculaire
- 26062 Da
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ID gène
- 4601
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UniProt
- P50539
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Pathways
- Maintenance of Protein Location
Antigène
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