TNNI2 anticorps (N-Term)

N° du produit ABIN2798893

Cet anticorps Lapin Polyclonal détecte spécifiquement TNNI2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TNNI2 anticorps (N-Term) (ABIN2798893)

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNNI2 anticorps

Épitope: AA 1-30, N-Term

Fonction: Rabbit Anti-Human TNNI2 (N-term) Antibody

Immunogène: This TNNI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from human skeletal muscle tissue lysate, using TNNI2 Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur TNNI2

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Autre désignation: TNNI2

Sujet:

Target Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Gene Symbol: TNNI2

Poids moléculaire: 21339 Da

ID gène: 7136

UniProt: P48788