SIGLEC6 anticorps (N-Term)

N° du produit ABIN2798979

Cet anticorps anti-SIGLEC6 est un anticorps Lapin Polyclonal détectant SIGLEC6 dans WB. Adapté pour Humain.

Aperçu rapide pour SIGLEC6 anticorps (N-Term) (ABIN2798979)

Antigène: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIGLEC6 anticorps

Épitope: AA 10-40, N-Term

Fonction: Rabbit Anti-Human SIGLEC6 (N-term) Antibody

Immunogène: This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human SIGLEC6.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of SIGLEC6 Antibody (N-term) was detected using the purified Pab.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur SIGLEC6

Antigène: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Autre désignation: SIGLEC6

Sujet:

Target Description: SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.

Gene Symbol: SIGLEC6

Poids moléculaire: 49913 Da

ID gène: 946

UniProt: O43699