KIDINS220 anticorps (C-Term)

N° du produit ABIN2798982

Cet anticorps anti-KIDINS220 est un anticorps Lapin Polyclonal détectant KIDINS220 dans WB. Adapté pour Humain.

Aperçu rapide pour KIDINS220 anticorps (C-Term) (ABIN2798982)

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIDINS220 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIDINS220 anticorps

Épitope: AA 1518-1547, C-Term

Fonction: Rabbit Anti-Human KIDINS220 (C-term) Antibody

Immunogène: This KIDINS220 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1518-1547 amino acids from the C-terminal region of human KIDINS220.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000KIDINS220 Antibody (C-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur KIDINS220

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Autre désignation: KIDINS220

Sujet:

Target Description: KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Gene Symbol: KIDINS220

Poids moléculaire: 196542 Da

ID gène: 57498

UniProt: Q9ULH0