EPO anticorps (Center)

N° du produit ABIN2799146

L’anticorps Lapin Polyclonal anti-EPO a été validé pour WB, FACS et IF. Il convient pour détecter EPO dans des échantillons de Humain.

Aperçu rapide pour EPO anticorps (Center) (ABIN2799146)

Antigène: EPO (Erythropoietin (EPO))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPO est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-EPO anticorps

Épitope: AA 329-357, Center

Fonction: Rabbit Anti-Human EPOR (Center) Antibody

Immunogène: This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50EPOR Antibody (Center) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.300 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur EPO

Antigène: EPO (Erythropoietin (EPO))

Autre désignation: EPO

Classe de substances: Hormone

Sujet:

Target Description: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Gene Symbol: EPOR

Poids moléculaire: 55065 Da

ID gène: 2057

UniProt: P19235

Pathways: Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity