POLE3 anticorps

N° du produit ABIN363202

Cet anticorps Souris Monoclonal détecte spécifiquement POLE3 dans WB, IF, IP et ICC. Il présente une réactivité envers Humain, Souris et Singe.

Aperçu rapide pour POLE3 anticorps (ABIN363202)

Antigène: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Reactivité: Humain, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp POLE3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 3C5-1

Détail du produit anti-POLE3 anticorps

Specificité: Reacts with DNA polymerase epsilon from human mouse, monkey, mink and hamster

Réactivité croisée (Details): Does not recognize DNA pol alpha, beta or delta. Does not reacts with Drosophilia or baculovirus host cell pol epsilon, and weakly, if at all, on S. cerivisae pol epsilon.

Purification: Purified (protein G)

Immunogène: Human DNA Polymerase epsilon purified from HeLa cells

Isotype: IgG2a

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF1:100, IP1:10-1:500, WB5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 16 mg/mL

Buffer: PBS

Stock: -20 °C/-80 °C

Stockage commentaire: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Détails sur POLE3

Antigène: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Autre désignation: DNA Polymerase epsilon Subunit 3

Sujet: Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.

ID gène: 54107

UniProt: Q9NRF9

Pathways: Réparation de l'ADN