Sca-1/Ly-6A/E anticorps (Biotin)

N° du produit ABIN2853588

L’anticorps Rat Monoclonal anti-Sca-1/Ly-6A/E a été validé pour FACS. Il convient pour détecter Sca-1/Ly-6A/E dans des échantillons de Souris.

Aperçu rapide pour Sca-1/Ly-6A/E anticorps (Biotin) (ABIN2853588)

Antigène: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Sca-1/Ly-6A/E est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: 238B

Détail du produit anti-Sca-1/Ly-6A/E anticorps (Biotin)

Specificité: This antibody reacts withSca-1.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein-G agarose

Immunogène: Mouse Sca-1 transfected LO cells

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur Sca-1/Ly-6A/E

Antigène: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Autre désignation: Ly6A/E / SCA1

Sujet: Sca-1 is a member of the Ly-6 antigen family which molecular mass of 8 kDa under non-reducing conditions and of 18 kDa under reducing conditions. Mouse hematopoietic stem cells express low levels of Thy-1 antigen (Thy-1lo) and to be negative for lineage markers (Lin-) that is, not expressing markers characteristic of B cells (B220), granulocytes (Gr-1), myelomonocytic cells (Mac-1) and T lymphocytes (CD4 and CD8). Recently, new monoclonal antibody, anti-Sca-1, was used to purify stem cells from the Thy-1lo, Linbone marrow subpopulation. Thy-1lo, Lin-, Sca-1+ (but not the Thy-1lo, Lin-, Sca-1-) population of bone marrow cells are highly purified pluripotent stem cells. They read out with nearly unit efficiency in assays for primitive myeloerythroid and thymic progenitor, and have a capability to admit lethally irradiated mouse to survive and be restored in all blood-cell lineages. The Thy-1lo, Lin-, Sca-1+ subpopulation thought to have all stem cells present in the bone marrow.Synonyms: Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP

ID gène: 110454

NCBI Accession: NP_034868

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation