Prostate Specific Antigen anticorps

N° du produit ABIN2853633

Cet anticorps Souris Monoclonal détecte spécifiquement Prostate Specific Antigen dans WB, IHC (p), IHC (fro) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Prostate Specific Antigen anticorps (ABIN2853633)

Antigène: Prostate Specific Antigen (PSA)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prostate Specific Antigen est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: CHYH2

Détail du produit anti-Prostate Specific Antigen anticorps

Specificité: This antibody detects normal prostate, benign prostate hyperplasia and prostate malignant carcinoma.

Purification: Affinity Chromatography on Protein G

Immunogène: Human Prostate Specific Antigen

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western blot: Concentration of 10 μg/mL MAb will allow visualization of 1 μg/lane of humanPSA. Immunohistochemistry-formalin-fixed paraffin embedded and frozen tissue sections usingABC immunoperoxidase assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with double distillated water to a final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.0 without preservatives

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur Prostate Specific Antigen

Antigène: Prostate Specific Antigen (PSA)

Autre désignation: Kallikrein-3 / PSA / KLK3

Sujet: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase

ID gène: 354

NCBI Accession: NP_001025218

UniProt: P07288

Pathways: Système du Complément