Septin 2 anticorps

N° du produit ABIN2854352

Détail du produit anti-Septin 2 anticorps

Antigène: Septin 2 (SEPT2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Septin 2 (septin 2)
Septin 2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Septin 2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: U87-MG , SK-N-SH

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: septin 2 (SEPT2 Produits)

Synonymes: anticorps DIFF6, anticorps NEDD5, anticorps Pnutl3, anticorps hNedd5, anticorps AW208991, anticorps Nedd-5, anticorps Nedd5, anticorps mKIAA0158, anticorps Vesp11, anticorps nedd5, anticorps wu:fb52g01, anticorps wu:fb99a01, anticorps Septin-2A, anticorps Septin-A, anticorps diff6, anticorps pnutl3, anticorps sept2, anticorps septa, anticorps xlsepta, anticorps SEPT2, anticorps Sep-02, anticorps Septin-2B, anticorps hnedd5, anticorps sept2-B, anticorps Septin-2, anticorps septin 2, anticorps septin 2 L homeolog, anticorps septin 2-like, anticorps COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain, anticorps septin 2 S homeolog, anticorps SEPT2, anticorps Sept2, anticorps sept2, anticorps sept2.L, anticorps SEPT2L, anticorps sepT2, anticorps sept2.S

Sujet: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Cellular Localization: Cytoplasm , Spindle

Poids moléculaire: 41 kDa

ID gène: 4735

UniProt: Q15019