Perforin 1 anticorps (N-Term)
-
- Antigène Voir toutes Perforin 1 (PRF1) Anticorps
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
-
Épitope
- N-Term
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Perforin 1 est non-conjugé
-
Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Attributs du produit
-
Rabbit polyclonal antibody to Perforin 1 (perforin 1 (pore forming protein))
Perforin 1 antibody [N1N3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human Perforin 1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product PRF1 Anticorps primaire
-
-
- Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
-
Positive Control: HepG2
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.37 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Antigène
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
- Autre désignation
- perforin 1 (PRF1 Produits)
- Synonymes
- anticorps FLH2, anticorps HPLH2, anticorps P1, anticorps PFN1, anticorps PFP, anticorps PRF1, anticorps Pfn, anticorps Pfp, anticorps Prf-1, anticorps Cyta, anticorps RATCYTA, anticorps LOC443187, anticorps perforin, anticorps prf1, anticorps cytolysin, anticorps perforin-1, anticorps perforin-1-like, anticorps perforin 1, anticorps perforin 1 (pore forming protein), anticorps perforin, anticorps perforin 1 L homeolog, anticorps PRF1, anticorps Prf1, anticorps LOC443187, anticorps prf1, anticorps prf1.L
- Sujet
-
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
Cellular Localization: Cytoplasmic granule membrane, Multi-pass membrane protein - Poids moléculaire
- 61 kDa
- ID gène
- 5551
- UniProt
- P14222
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
-