CDKN2D anticorps
Aperçu rapide pour CDKN2D anticorps (ABIN2854392)
Antigène
Voir toutes CDKN2D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Attributs du produit
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Rabbit Polyclonal antibody to p19 INK4d (cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4))
p19 INK4d antibody -
Purification
- Affinity purified by Protein A.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human p19 INK4d. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Rat bone marrow
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2 mg/mL
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Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))
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Autre désignation
- cyclin dependent kinase inhibitor 2D
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Sujet
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The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
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Poids moléculaire
- 18 kDa
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ID gène
- 1032
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UniProt
- P55273
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Pathways
- Cycle Cellulaire, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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