MUTYH anticorps (Center)

N° du produit ABIN2854424

L’anticorps Lapin Polyclonal anti-MUTYH a été validé pour WB. Il convient pour détecter MUTYH dans des échantillons de Humain et Souris.

Aperçu rapide pour MUTYH anticorps (Center) (ABIN2854424)

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUTYH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MUTYH anticorps

Épitope: Center

Attributs du produit: Rabbit polyclonal antibody to MYH (mutY homolog (E. coli))
MUTYH antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human MUTYH. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , NIH-3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.39 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur MUTYH

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Autre désignation: MUTYH

Sujet: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Nucleus

Poids moléculaire: 60 kDa

ID gène: 4595

Pathways: Réparation de l'ADN