UNG anticorps

N° du produit ABIN2854428

Cet anticorps anti-UNG est un anticorps Lapin Polyclonal détectant UNG dans WB et IHC (wm). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour UNG anticorps (ABIN2854428)

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Whole Mount) (IHC (wm))

Détail du produit anti-UNG anticorps

Réactivité croisée: Humain, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to UNG (uracil-DNA glycosylase)
UNG antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human UNG. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-UNG (ABIN2854428)

Wu, Chen, Sun, Wu, Jia, Meng: "Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo." dans: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15463-73, (2014) (PubMed).

Détails sur UNG

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Autre désignation: uracil DNA glycosylase

Sujet: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2.

Cellular Localization: Isoform 1: Mitochondrion , Isoform 2: Nucleus

Poids moléculaire: 35 kDa

ID gène: 7374

UniProt: P13051

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response