UNG anticorps

N° du produit ABIN2854428

Détail du produit anti-UNG anticorps

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Whole Mount) (IHC (wm))

Réactivité croisée: Humain, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to UNG (uracil-DNA glycosylase)
UNG antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human UNG. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-UNG (ABIN2854428)

Wu, Chen, Sun, Wu, Jia, Meng: "Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo." dans: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15463-73, (2014) (PubMed).

Détails sur UNG

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Autre désignation: uracil DNA glycosylase (UNG Produits)

Synonymes: anticorps DGU, anticorps HIGM4, anticorps HIGM5, anticorps UDG, anticorps UNG1, anticorps UNG15, anticorps UNG2, anticorps ung, anticorps zgc:56102, anticorps PSPTO4236, anticorps BA5648, anticorps ECK2578, anticorps JW2564, anticorps An02g14790, anticorps AO090001000732, anticorps DDBDRAFT_0204444, anticorps DDBDRAFT_0214910, anticorps DDB_0204444, anticorps DDB_0214910, anticorps uracil-DNA glycosylase, anticorps uracil DNA glycosylase, anticorps uracil DNA glycosylase a, anticorps uracil-DNA glycosylase Ung, anticorps uracil-DNA-glycosylase, anticorps uracil DNA glycosylase L homeolog, anticorps uracil glycosylase, anticorps temporal expression: early, anticorps ung, anticorps ung2, anticorps Ung, anticorps UNG, anticorps unga, anticorps STY2840, anticorps ung.L, anticorps ANI_1_3358024, anticorps AOR_1_1318164, anticorps uglA, anticorps Arnit_2731, anticorps D4R

Classe de substances: Viral Protein

Sujet: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2.

Cellular Localization: Isoform 1: Mitochondrion , Isoform 2: Nucleus

Poids moléculaire: 35 kDa

ID gène: 7374

UniProt: P13051

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response