DUSP14 anticorps (C-Term)

N° du produit ABIN2854481

L’anticorps Lapin Polyclonal anti-DUSP14 a été validé pour WB. Il convient pour détecter DUSP14 dans des échantillons de Humain.

Aperçu rapide pour DUSP14 anticorps (C-Term) (ABIN2854481)

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP14 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUSP14 anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to MKP-6 (dual specificity phosphatase 14)
MKP-6 antibody [C2C3], C-term

Purification: Affinity purified by Protein A.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP14. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: MKP-6 transfected 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur DUSP14

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Autre désignation: dual specificity phosphatase 14

Sujet: In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80, MIM 112203) and B7-2 (CD86, MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2, MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4, MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM]

Poids moléculaire: 22 kDa

ID gène: 11072

UniProt: O95147