HRH3 anticorps (C-Term)

N° du produit ABIN2854644

Détail du produit anti-HRH3 anticorps

Antigène: HRH3 (Histamine Receptor H3 (HRH3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Histamine H3 Receptor (histamine receptor H3)
Histamine H3 Receptor antibody

Purification: Affinity purified by Protein A.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Histamine H3 Receptor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431 , H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-HRH3 (ABIN2854644)

Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." dans: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

Détails sur HRH3

Antigène: HRH3 (Histamine Receptor H3 (HRH3))

Autre désignation: histamine receptor H3 (HRH3 Produits)

Synonymes: anticorps GPCR97, anticorps HH3R, anticorps AW049250, anticorps H3R, anticorps histamine receptor H3, anticorps HRH3, anticorps Hrh3

Sujet: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Poids moléculaire: 49 kDa

ID gène: 11255

UniProt: Q9Y5N1

Pathways: cAMP Metabolic Process, Feeding Behaviour