FANCC anticorps (Center)

N° du produit ABIN2854743

Détail du produit anti-FANCC anticorps

Antigène: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to FANCC (Fanconi anemia, complementation group C)
FANCC antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human FANCC. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , NIH-3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.989 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-FANCC (ABIN2854743)

Pan, Wang, Chen, Ding, Jiang, Gao, Mo, Huang, Lou, Cao: "Deleterious Mutations in DNA Repair Gene FANCC Exist in BRCA1/2-Negative Chinese Familial Breast and/or Ovarian Cancer Patients." dans: Frontiers in oncology, Vol. 9, pp. 169, (2019) (PubMed).

Détails sur FANCC

Antigène: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Autre désignation: FANCC (FANCC Produits)

Synonymes: anticorps zgc:154105, anticorps FANCC, anticorps fa3, anticorps fac, anticorps facc, anticorps FA3, anticorps FAC, anticorps FACC, anticorps BB116513, anticorps Facc, anticorps Fanconi anemia complementation group C, anticorps Fanconi anemia, complementation group C, anticorps Fanconi anemia complementation group C L homeolog, anticorps FANCC, anticorps fancc, anticorps fancc.L, anticorps Fancc

Sujet: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Cellular Localization: Nucleus , Cytoplasm

Poids moléculaire: 63 kDa

ID gène: 2176

Pathways: Réparation de l'ADN