Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) anticorps
Aperçu rapide pour Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) anticorps (ABIN2854768)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée
- Boeuf (Vache), Porc
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Réactivité croisée (Details)
- Mouse (81 %), Pig (83 %), Bovine (88 %)
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Attributs du produit
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Rabbit Polyclonal antibody to ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain)
ACADM antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human ACADM. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , A431 , HeLa , HepG2 , Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.74 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)
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Autre désignation
- ACADM
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Sujet
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This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Mitochondrion matrix -
Poids moléculaire
- 47 kDa
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ID gène
- 34
Antigène
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