Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Center) anticorps

N° du produit ABIN2854769

L’anticorps Lapin Polyclonal anti- a été validé pour WB, IF, IHC (p) et ICC. Il convient pour détecter dans des échantillons de Humain, Souris et Rat. Il y a 1 publication disponible.

Aperçu rapide pour Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Center) anticorps (ABIN2854769)

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit

Épitope: Center

Attributs du produit: Rabbit Polyclonal antibody to ACADM (acyl-CoA dehydrogenase, C-4 to C-12 straight chain)
ACADM antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ACADM. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: Molt-4 , Neuro2A , GL261 , C8D30 , PC-12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Référence

Jernberg, Bowman, Wolfgang, Scafidi: "Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain." dans: Journal of neurochemistry, Vol. 142, Issue 3, pp. 407-419, (2017) (PubMed).

Détail du antigène

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

Autre désignation: ACADM

Sujet: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Mitochondrion matrix

Poids moléculaire: 47 kDa

ID gène: 34